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pentobarbital will minimize the extent or effect of doravirine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will decrease the extent or result of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Powerful CYP3A4 inducers may well decrease part